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Hello all,

I have read the article. I am confused since it is written that .. the variability of lesion intensity on T1-weighted image does not deteriorate the segmentation of lesions and ... In addition to this multichannel weighting scheme, we further enhance the clustering model using the approach described by Roy et al. (2008) to particularly improve accuracy on (MPRAGE) T1-weighted images.

We have 3D T1 in a few patients. If you use the 3D T1 images for co-registration or gray/white matter segmentation, I could try to use the 3D MRI scout (3D calibration scans, blurry image with T1 contrast displayed as a separate series) instead of the 3D T1. As far as I understood you don't use 3D T1 just for registration or gray/white matter segmentation. Am I right?

2)How about reliable range, can we use other 3d T1 (vibe etc)?

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