mrcieu Goto Github PK

mdnlr-and-rheumatoid-arthritis-script

Rheumatoid arthritis (RA) is a disease of chronic systemic inflammation (SI). In the present study, we used four datasets to explore whether methylation-derived neutrophil-to-lymphocyte ratio (mdNLR) might be a marker of SI in new onset, untreated, and treated prevalent RA cases and/or a marker of treatment response to the tumour necrosis factor inhibitor (TNFi) etanercept.

measurement_error_adjustment

Code accompanying paper on exploring regression dilution bias using repeat measures in UK Biobank

melodi

Mining Enriched Literature Objects to Derive Intermediates

melodi-presto

A fast and programmatic MELODI

mendelvar_standalone

Standalone version of the MendelVar pipeline

met-d-import

UKBB Nightingale import to OpenGWAS

met-e-import

metaboprep

a pipeline of metabolomics data processing and quality control

mr-base-paper

mr-e-values

Code to calculate effect estimates and descriptive statistics to be used as inputs for the MR-E-Values shiny app (https://mark-gibson.shinyapps.io/mr-e-values_shiny_app/), using the applied example of the potential causal effect of smoking behaviour on schizophrenia.

mr-lit

mr-maternal-smoking

Analysis code for proxy gene-by-environment Mendelian randomization of maternal smoking on offspring health

mr-preg

Repository for the MR-PREG collaboration

mr-randomization-test

mr-uganda-hackathon-2023-2

mr-uganda-hackathon-2023-6

Group 6 project

mrbase_casestudies

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes

mrc_uganda_hackathon_202306_group4

MRC Uganda MR short course Hackathon Project Group 4

mrcieu.r-universe.dev

R packages for mrcieu.r-universe.dev

mrever

mrever: R package to query MR-EvE Neo4j database

mrinstruments

Data objects for various sets of instruments

mrtwin_power

multiversemr_smoking_schizophrenia

Code to apply a multiverse Mendelian randomisation approach to the example of the potential causal effect of smoking behaviour on schizophrenia.

mvmralcsmo

A repository of code for a MVMR study of the effect of alcohol and smoking on lung function

oci-elastic

IEU version of https://github.com/cloud-partners/oci-elastic

ood_opengwasutils

Utilities for using Oracle Open Data version of OpenGWAS

opengwas

opengwas-api

API for MRC-IEU OpenGWAS platform (https://gwas.mrcieu.ac.uk)

opengwas-infpval-fix

Documentation and fixes for p-value issues for some datasets

opengwas-manual-uploads

Collection of scripts for manually added datasets to OpenGWAS