korcsmarosgroup / tflink

Repository for the TFlink.net website.

TFlink

This github repo contains the source code of the TFLink website.

TFLink gateway uniquely provides comprehensive and highly accurate information on transcription factor - target gene interactions, nucleotide sequences and genomic locations of transcription factor binding sites for human and six model organisms: mouse (Mus musculus), rat (Rattus norvegicus), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), nematode (Caenorhabditis elegans), and yeast (Saccharomyces cerevisiae). TFLink contains clearly identified data, and provides information about the sources: databases, experimental methods and publications. To create TFLink, we examined the large transcription factor databases, and selected ten resources for integration: DoRothEA, GTRD, HTRIdb, JASPAR, ORegAnno, REDfly, ReMap, TRED, TRRUST, and Yeastract. By exploiting these database sources, we integrated accurate, small-scale experimental data and the results of large-scale experiments.