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geneticresources buleiba wanglu205 remlapmot adams-charleen jjmpal sangyoonstat nsandau

mrmix's Issues

Inquiry on the run time of MRMix()

May I ask if it is normal for me to run MRMix() in R language for three hours without any results? I have observed that the computer's memory usage is wavy. The screenshot has been attached.

4f184f01d7a3c28d3026eee6993cd71

Algorithm may not have converged

Hi Guanghao,

Recently I found that MRmix sometimes gives very significant P-value along with the following information:

> MRMix(bzx, bzy, sx=bzx_se, sy=bzy_se, theta_temp_vec = seq(-1,1,by=0.01))
$theta
[1] -0.09

$pi0
[1] 0.9999

$sigma2
[1] 5.662289e-05

$SE_theta
[1] 0.02252094

$zstat_theta
[1] -3.99628

$pvalue_theta
[1] 6.434561e-05

Warning message:
In MRMix(bzx, bzy, sx = bzx_se, sy = bzy_se, theta_temp_vec = seq(-1,  :
  Algorithm may not have converged.

I was wondering how should I interpret this result. And is there any way to make it converged and provide more robust estimate?

Thank you!

Cheers,
Angli

Error : bad restore file magic number

Hi,

I tried to install the package but got errors like below,

> devtools::install_local("MRMix-master.zip")
Installing package into ‘/R/x86_64-pc-linux-gnu-library/3.2’
(as ‘lib’ is unspecified)
* installing *source* package ‘MRMix’ ...
** R
** data
*** moving datasets to lazyload DB
Warning: file ‘BMI15_MDD18.RData’ has magic number 'RDX3'
  Use of save versions prior to 2 is deprecated
Error : bad restore file magic number (file may be corrupted) -- no data loaded
ERROR: lazydata failed for package ‘MRMix’
* removing ‘/R/x86_64-pc-linux-gnu-library/3.2/MRMix’
Error: Failed to install 'MRMix-master.zip' from local:
  (converted from warning) installation of package ‘/RtmpExLT8m/remotes327a172e97f4/MRMix-master’ had non-zero exit status

I have also tried other ways to install the package but none works. Do you have any solution to that?

Thanks!
Alex

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