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In this project the PKPD properties of Erlotinib and Gefitinib are investigated.

License: BSD 3-Clause "New" or "Revised" License

Jupyter Notebook 99.82% Python 0.18%

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erlotinibgefitinib's Issues

Create pkpd.error base class and Constant, Multiplicative and Combined Error classes

The inference of the structural + error model can be straightforwardly performed using pints.ProblemLogLikelihoods. However, forward simulation of the error appears to be rather cumbersome with the Likelihoods.

A straightforward solution is to implement Error classes for forward simulation by wrapping scikit statistical models. Those models should be able to produce random samples as well as compute percentiles.

With this issue also the corresponding pkpd.plots.plot_error function should be refactored.

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