cabsel / connectome-rewiring

Connectome-Rewiring

This repository provides the codes for three key analysis in the manuscript:

S Meamardoost, EJ Hwang, M Bhattacharya, C Ren, L Wang, C Mewes, Y Zhang, T Komiyama, R Gunawan. Rewiring dynamics of functional connectome in motor cortex during motor skill learning. bioRxiv, 499746, 2022. doi:10.1101/2022.07.12.499746

PCA Rewiring

This folder includes MATLAB codes for Principal Component Analysis of functional connectomes during motor skill learning. The functional connectomes were reconstructed via partial correlations using the tool FARCI.

Connectome Activity vs Motor Performance

This folder includes the codes for the analysis of trial-based functional connectome activity and its association with motor performance improvements. The subfolder "Cue to reward surface plot" contains MATLAB codes to generate surface plot of cue-to-reward times versus PC1 and PC2 of trial-based functional connectome activity. Pseudotime analysis code is provided as a Jupyter Notebook file.

Linear Decoders

This folder includes MATLAB codes for linear movement decoders for Core, Early Phase, Late Phase and Other neurons. The neuronal spikes data ('all_spikes.mat') can be downloaded from here.