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MitoHEAR (Mitochondrial HEteroplasmy AnalyzeR) is an R package that allows the estimation as well as downstream statistical analysis of the mtDNA heteroplasmy calculated from single-cell datasets.

Home Page: https://scialdonelab.github.io/MitoHEAR/

License: GNU General Public License v3.0

TeX 4.84% R 95.16%
bioinformatics-analysis heteroplasmy open-source rstats-package

mitohear's People

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batoolmm avatar csoneson avatar danielskatz avatar gabrielelubatti avatar

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batoolmm csoneson

mitohear's Issues

Add URL to the description of the package

I like the Vignettes created with pkgdown (openjournals/joss-reviews#4265), but it's hidden in the README. Usually, the Vignettes URL is added to the description in the top right of the repo. It makes it more visible and gives a quick summary/overview of the package, especially when you search on GitHub. Below is how I do recommend it:

Yours show as:

Screenshot 2022-05-08 at 14 47 26

We recommend including the URL and a few words about the package:

Screenshot 2022-05-08 at 14 49 43

Again, this is not necessary but it's a good practice!

Increase the readability of the code in the README

Thank you for all the changes you made to the repo (openjournals/joss-reviews#4265), I love the changes you made to the README .

Just a simple tip when adding code to the READEM - in order to increase the readability, we recommend highlighting the syntax by defining the language in code block ( e.g. ```r )

For example

current_wd <- getwd()
url <- "https://hmgubox2.helmholtz-muenchen.de/index.php/s/7P9C57RxfKnH5Qx/download/input_bam_files.tar.gz"
destfile <- paste0(current_wd, "input_bam_files.tar.gz")
download.file(url, destfile, quiet = FALSE)
untar(destfile, exdir=current_wd)

load(system.file("extdata", "after_qc.Rda", package = "MitoHEAR"))
cell_names <- as.vector(after_qc$new_name)
cell_names <- cell_names[1:5]
cell_names[1:5]
[1] "24538_8_14" "24538_8_23" "24538_8_39" "24538_8_40" "24538_8_47"

will be:

current_wd <- getwd()
url <- "https://hmgubox2.helmholtz-muenchen.de/index.php/s/7P9C57RxfKnH5Qx/download/input_bam_files.tar.gz"
destfile <- paste0(current_wd, "input_bam_files.tar.gz")
download.file(url, destfile, quiet = FALSE)
untar(destfile, exdir=current_wd)

load(system.file("extdata", "after_qc.Rda", package = "MitoHEAR"))
cell_names <- as.vector(after_qc$new_name)
cell_names <- cell_names[1:5]
cell_names[1:5]
[1] "24538_8_14" "24538_8_23" "24538_8_39" "24538_8_40" "24538_8_47"

by only adding r in the code block!

It is not necessarily added, but it makes the code more readable!

An example of some editing to the README file with a table of content can be seen in my fork here

Thank you again for your work!

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