roche / global-hta-evidence-open

Collection of R Packages that support analysis for the purposes of Health Technology Assessment (HTA)

Global HTA Evidence Open

This repository contains links to code and analysis made open source from Global Access Evidence.

Rpackages

flexsurvPlus

This package facilitates performing survival analysis to support the creation of Excel based economic models by providing helper functions to use alongside the flexsurv package.

Repository	Documentation
https://github.com/Roche/flexsurvPlus	https://roche.github.io/flexsurvPlus

gemtcPlus

This package implements some convinience functions for perfoming Bayesian NMA using the gemtc package for standard models (binary data, hazard ratio data). It also contains some more advanced models for time-to-event data with time varying hazard ratios, such as fractional polynomial NMAs and piecewise exponential NMA models.

Repository	Documentation
https://github.com/Roche/gemtcPlus	https://roche.github.io/gemtcPlus

MAIC

This package facilitates performing matching-adjusted indirect comparison (MAIC) anaylsis for a disconnected treatment network where the endpoint of interest is either time-to-event (e.g. overall survival) or binary (e.g. objective tumor response).

Repository	Documentation
https://github.com/Roche/MAIC	https://roche.github.io/MAIC

rpsftmPlus

This package implements some convinience functions for working with the rpsftm package and general analysis of trials affected by treatment switching.

Repository	Documentation
https://github.com/Roche/rpsftmPlus	https://roche.github.io/rpsftmPlus

descem

This package facilitates performing discrete event simulations without resource constraints for cost-effectiveness analysis.

Repository	Documentation
https://github.com/Roche/descem	https://roche.github.io/descem