open-systems-pharmacology / fluvoxamine-tizanidine-ddi

Modeling of published clinical Fluvoxamine-Tizanidine-DDI studies for model evaluation

Fluvoxamine-Tizanidine-DDI

Modeling of published clinical Fluvoxamine-Tizanidine-DDI studies for model evaluation.

The repository contains a PK-Sim snapshot (*.json) file containing the respective simulations.

The latest release of the snapshot can be found here.

The reference model repositories can be found here:

• Fluvoxamine OSP PBPK model
• Tizanidine OSP PBPK model

Contacts

For your questions and comments about the models please create a new issue. A full publication about models presented is available at: https://www.mdpi.com/1999-4923/12/12/1191 .

Code of conduct

Everyone interacting in the Open Systems Pharmacology community (codebases, issue trackers, chat rooms, mailing lists etc...) is expected to follow the Open Systems Pharmacology code of conduct.

Contribution

We encourage contribution to the Open Systems Pharmacology community. Before getting started please read the contribution guidelines. If you are contributing code, please be familiar with the coding standard.

License

The model code is distributed under the GPLv2 License.https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/psp4.12397)