The application allows users to calculate PSA velocity using three methods from Methods of calculating prostate-specific antigen velocity. Connolly D, et.al.
- Arithmetic equation of change in PSA over time (AE)
- Linear regression (LR)
- Rate of PSA change using first and last values only (FL)
The source code and installation instructions for PSAV are available at https://github.com/oncogenetics/PSAV.
PSAV is made available under the MIT license.
install.packages(c("shiny","ggplot2","DT","dplyr","MASS","markdown"), dependencies = TRUE)
- Online: https://zx8754.shinyapps.io/PSA_Velocity/
- Locally using R console: To start PSAV, open R (RStudio recommended), copy the following code into the console and hit Return:
library(shiny)
runGitHub("PSAV", "oncogenetics")
The IMPACT study: Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in men at higher genetic risk and controls
Prostate-Specific Antigen Velocity as a Predictive Biomarker in a Prospective Prostate Cancer Screening Study of Men with Genetic Predisposition
Christos Mikropoulos1+, Christina G. Selkirk3+, Sibel Saya1 , Elizabeth Bancroft2, Tokhir Dadaev1, Charles Brendler3, Daniel A. Leongamornlert1, Elizabeth Page1, Natalie Taylor2, Edward Saunders1, Clara Cieza-Borrella1, Alexander Dias1, The IMPACT study collaborators, Sue Moss, Zsofia Kote-Jarai1, Brian T. Helfand3++, Rosalind A. Eeles1,2++
- The Institute of Cancer Research, 15 Cotswold Road, London, UK
- The Royal Marsden NHS Foundation Trust, London, UK
- Northshore University Health System, Evanston, Illinois, USA
+Joint first Authors, ++Joint Senior Authors
Questions, suggestions, and bug reports are welcome and appreciated.
- Submit suggestions and bug-reports
- Contact email [T.Dadaev](mailto: [email protected])
https://github.com/oncogenetics/PSAV/issues
This application was created by T.Dadaev and Prof.R.Eeles team.