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Minimal cell model (Av-Ron et al 1991)
Home Page: https://modeldb.science/42047
The Minimal Cell Model (MCM) : Av-Ron, E, Parnas, H, Segel, LA (1991) A minimal biophysical model for an excitable and oscillatory neuron. Biol. Cybern. 65:487-500 implemented in SNNAP (http://snnap.uth.tmc.edu). The minimal cell model (MCM) is a reduced Hodgkin-Huxley model that can exhibit excitable and oscillatory behavior. It consists of two ordinary differential equations, dV/dt for membrane voltage and dW/dt for potassium activation and sodium inactivation. The MCM has a stable membrane potential of -60mV. With constant input current of 10uA/cm2, it exhibits oscillations of 150Hz. It is based on the work by FitzHugh and Rinzel. Provided by Evyatar Av-Ron <[email protected]> To run: Download and unzip the zip file into a directory that has no spaces in its path. Double click on the SNNAP8.jar file (where the 8 might be a different version) Click on start simulation, then File--> Load simulation and browse to the MCM folder and select the MCM.smu file. Finally click on start.
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