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Generates sample-specific protein databases from raw peptide spectra

License: BSD 2-Clause "Simplified" License

Dockerfile 0.16% Python 80.45% Shell 0.71% Jupyter Notebook 18.67%

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kaiko_metaproteome's Issues

Improve detail of Kaiko output

Add more detail to the output and intermediate files of kaiko. Number of proteins per taxa, taxa dependency.

This will allow us to consider more complex logic when building the FASTA file.

Create FastAPI framework for Kaiko

Create FastAPI functions to help with deployment of Kaiko into existing workflows.

Details to follow as we get closer to finishing Kaiko, add them here.

Improve denovo sequencing model in Kaiko

The current model is from ~2017. Current transformer based models may give us huge improvements in denovo identification.

This would be a more open ended path. Thankfully, we can use denovo sequencing model within Kaiko.

Benchmarking of FASTA file

Use X-Tandem quick search to test how well raw spectra protein search performs with a particular taxa.

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