lihm1 / pc_cna_signature

Prostate Cancer Alteration Signature Analysis https://xsliulab.github.io/PC_CNA_signature/

Prostate Cancer Alteration Signature Analysis Report

Read online analysis report at https://xsliulab.github.io/PC_CNA_signature/.

• tool sigminer: https://shixiangwang.github.io/sigminer-doc/
• manuscript: Wang S, Li H, Song M, Tao Z, Wu T, He Z, et al. (2021) Copy number signature analysis tool and its application in prostate cancer reveals distinct mutational processes and clinical outcomes. PLoS Genet 17(5): e1009557. https://doi.org/10.1371/journal.pgen.1009557

The both methods ("Wang" and "Macintyre") are available at Sigminer v1.2.5 (https://cran.r-project.org/src/contrib/Archive/sigminer/).

For reproducing the Cox result shown in manuscript, please refer to this script.

LICENSE

MIT ©2020 Shixiang Wang, Huimin Li, Xuan Wang, Minfang Song and Xue-Song Liu

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Cancer Biology Group @ShanghaiTech

Research group led by Xue-Song Liu in ShanghaiTech University