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Epigenome-wide analysis of DNA methylation from Alzheimer's patients and unaffected controls

License: MIT License

R 100.00%
alzheimers-disease dna-methylation 450k epigenomics

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alzheimers_dnam's Issues

Questions for Alzheimers_DNAm paper

Thank you for upload the code of the article “Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease”. It really helps a lot!

However, I could not find the function “dmrPlot” in “03b_caseControl_DMR_plots.R” . Could you help me? I am looking forward to hear from you.

Gene expression data in GEO

Alzheimers_DNAm/GEO/readme.txt

Line 20 in 5bb82e9

All of the data submitted to GEO for DNAm includes data from 269 tissue samples generated from 74 postmortem brain donors. The subset of 264 tissue samples with corresponding count data for expressed genes from RNA-sequencing data is also provided.

Thanks for this interesting work! I cannot find the gene expression data in GSE125895. Do you have a separate GSE for sharing the gene expression data? Thanks!

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