Coder Social home page Coder Social logo

jwatowatson / sars-cov2-viral-clearance-kinetics Goto Github PK

View Code? Open in Web Editor NEW
0.0 1.0 0.0 605.85 MB

Pharmacodynamic summary statistics of viral clearance for phase 2 trials

License: Creative Commons Attribution 4.0 International

R 0.22% Stan 0.20% HTML 99.57% Shell 0.01%

sars-cov2-viral-clearance-kinetics's Introduction

SARS-CoV2-Viral-Clearance-Kinetics

Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric Studies.

This repository accompanies our [publication in AAC]{https://doi.org/10.1128/aac.00192-22}.

This is an analysis of openly available serial viral load data from the NBA bubble. We fit a series of simple viral kinetics models; show that clearance is bi-exponential; and then show that directly estimating rate of clearance under a log-linear model is a superior endpoint as compared to time to clearance for intervention studies of antiviral agents.

sars-cov2-viral-clearance-kinetics's People

Contributors

jwatowatson avatar

Watchers

avatar

Recommend Projects

  • React photo React

    A declarative, efficient, and flexible JavaScript library for building user interfaces.

  • Vue.js photo Vue.js

    🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.

  • Typescript photo Typescript

    TypeScript is a superset of JavaScript that compiles to clean JavaScript output.

  • TensorFlow photo TensorFlow

    An Open Source Machine Learning Framework for Everyone

  • Django photo Django

    The Web framework for perfectionists with deadlines.

  • D3 photo D3

    Bring data to life with SVG, Canvas and HTML. 📊📈🎉

Recommend Topics

  • javascript

    JavaScript (JS) is a lightweight interpreted programming language with first-class functions.

  • web

    Some thing interesting about web. New door for the world.

  • server

    A server is a program made to process requests and deliver data to clients.

  • Machine learning

    Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.

  • Game

    Some thing interesting about game, make everyone happy.

Recommend Org

  • Facebook photo Facebook

    We are working to build community through open source technology. NB: members must have two-factor auth.

  • Microsoft photo Microsoft

    Open source projects and samples from Microsoft.

  • Google photo Google

    Google ❤️ Open Source for everyone.

  • D3 photo D3

    Data-Driven Documents codes.