jiayuewan / booster_effectiveness

Code repository for paper studying booster effectiveness against COVID-19 infections, published in PLOS Medicine.

Booster vaccination protection against SARS-CoV-2 infections in young adults during an Omicron-predominant period: a retrospective cohort study

This is the code repository for our paper: Booster vaccination protection against SARS-CoV-2 infections in young adults during an Omicron-predominant period: a retrospective cohort study, published in PLOS Medicine.

Citation for the paper

Wan J, Cazer CL, Clarkberg ME, Henderson SG, Lee SE, et al. (2023) Booster vaccination protection against SARS-CoV-2 infections in young adults during an Omicron BA.1-predominant period: A retrospective cohort study. PLOS Medicine 20(1): e1004153. https://doi.org/10.1371/journal.pmed.1004153

@article{10.1371/journal.pmed.1004153,
    doi = {10.1371/journal.pmed.1004153},
    author = {Wan, Jiayue AND Cazer, Casey L. AND Clarkberg, Marin E. AND Henderson, Shane G. AND Lee, Scarlett E. AND Meredith, Genevive R. AND Osman, Marwan AND Shmoys, David B. AND Frazier, Peter I.},
    journal = {PLOS Medicine},
    publisher = {Public Library of Science},
    title = {Booster vaccination protection against SARS-CoV-2 infections in young adults during an Omicron BA.1-predominant period: A retrospective cohort study},
    year = {2023},
    month = {01},
    volume = {20},
    url = {https://doi.org/10.1371/journal.pmed.1004153},
    pages = {1-19},
    number = {1},
}

Brief overview

In the paper we sought to estimate the effectiveness of COVID-19 boosters in reducing SARS-CoV-2 infections in the vaccinated population of students in a period (December 5 - December 31, 2021) during which there was an explosive increase in Omicron cases to the point where the Omicron variant (BA.1) became predominant at Cornell University’s Ithaca campus. We leveraged polymerase chain reaction (PCR) testing data derived from a SARS-CoV-2 surveillance program that required mandatory routine SARS-CoV-2 testing of students and departure tests before students left the Ithaca campus.