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Bio-ModelChecker: Using Bounded Constraint Satisfaction to Seamlessly Integrate Observed Behavior with Prior Knowledge of Biological Networks

C++ 43.03% Python 56.97%
networks-biology synthetic-biology thomas-network multivalued-logic multivalued-network constraint-satisfaction constraint-programming learning-networks evolutionary-biology

biomodelchecker's Introduction

👨🏻‍💻  About Me

💡  I like to explore new technologies related to ML, Signal processing and DeepLearning and build cool products.
🌱  I'm a senior lead data scientist.
✍️  In my free time, I like playing football, solving puzzles and do competitive programming.
📫  How to reach me https://hooman650.github.io/

Bear coder


🛠  Tech Stack

Python  JavaScript  Java  C  C++  Bootstrap
HTML  CSS  Git  GitHub  Markdown
Visual Studio Code  Eclipse

🧠  DL Stack

PyTorch scikit-learn Keras SciPy TensorFlow


⚙️  GitHub Analytics


🤝🏻  Connect with Me

biomodelchecker's People

Contributors

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biomodelchecker's Issues

General Requests and Enhancements

Feature Request and enhancement

This is an attempt to track the enhancements and feature requests in BioModelChecker 🔉 🔬
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  • If a model only contains Steady State constrains and no Trajectory, BioMC does not import its solutions properly (reported by JohnC)
  • Import solutions from multiple folders
  • Check the input json file and check whether length of Trajectory matches the number of entities
  • Allow constraints for "rest" value of each node (decay)
  • Match states in output trajectories to input (which states are added automatically by model checker?)
  • Select SS1 or SS2 from competing models as MIS targets
  • The tool does not run properly with its shortcut desktop version (e.g. path-issue)
  • Parse K matrix to display truth tables for each node (e.g. Output a multivalued logical equation)
  • Identify available node-steady states supported by a given parameter set (SS detection)
  • Identify oscillatory attractors
  • Identify failed constraints (specific causes of unsatisfiability)

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🚣 🚛

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