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Time consumming workflow about ms-cleanr HOT 2 CLOSED

emetabohub avatar emetabohub commented on August 22, 2024
Time consumming workflow

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Comments (2)

guikool avatar guikool commented on August 22, 2024

Dear Darius,
sorry for the late reply
indeed it will largely depend on dataset size in input
For instance, if the output from MSdial are above thousands of features, it may be very long.
As a rule of thumb, for orbitrap, use 100000 to 500000 as threshold value in MSdial, use 1000 to 10000 for QTOF based detector.
If you encounter more than 1000 features after MSdial, increase your threshold.
Best regards
G.

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guikool avatar guikool commented on August 22, 2024

Another thing to consider is your feature RSD treshold set at "80" which seems really high, a value around "40" is more suitable

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