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Gene-set Association analysis Using Sparse Signals
Dear GAUSS team,
When downloading pathway information from GSEA e.g. https://www.gsea-msigdb.org/gsea/msigdb/human/collections.jsp#C2 their third column is tab seperated, whereas GAUSS requires comma separated files for the third column.
In R I have tried:
x$genesets <- gsub("\t",",")
but this does not work.
Do you have a one liner that can turn these files into GAUSS useable ones?
Many thanks
Hi, thanks for sharing this project!
Were the gene-level UK Biobank summary statistics used in the GAUSS preprint ever published? I was hoping to use this package to rerun different gene sets, ideally from the same initial gene-level analysis (from SKAT-Common-Rare presumably).
I didn't see any gene-level results at https://www.leelabsg.org/resources or the FTP server for nearly enough phenotypes, and I was expecting ~1,400 based on the preprint.
Any help would be much appreciated!
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