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R package with quasi-Monte Carlo methods to estimate mixed models commonly used for random effect structures from pedigrees.

R 3.44% TeX 0.27% C 0.17% C++ 8.98% Fortran 0.20% HTML 86.95%
generalized-linear-mixed-models probit threshold-model mixed-models pedigree importance-sampling quasi-monte-carlo graph-partitioning

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pedmod's Issues

Support weights

Implement support for case weights to:

  1. support weights when performing non-parametric bootstrap.
  2. support cases where there are only categorical variables and, thus, the potential that multiple log marginal likelihood terms are identical.

README should state that the unshared random effect variance is fixed

It might not be immidealty clear from these lines

pedmod/README.Rmd

Lines 43 to 50 in 051fc85

The $C_{il}$s are known scale/correlation matrices where each of the $l$'th
types correspond to a type of effect. A
typical example is that $C_{il}$ is two times the kinship matrix in which
case we call:
$$
\frac{\sigma_l^2}{1 + \sum_{k = 1}^K\sigma_k^2}
$$

that

  1. there is an unshared random effect.
  2. the scale parameter / variance for the unshared random effect is fixed to be one.

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