Prediction of Alzheimer's Disease Based on Deep Neural Network by Integrating Gene Expression and DNA Methylation Dataset
We developed gene expression and DNA methylation based Alzheimer's disease prediction algorithm using deep neural network.
https://github.com/ChihyunPark/DNN_for_ADprediction
Python 3.5
- numpy (1.16.3)
- pandas (0.24.2)
- scikit-learn (0.21.0)
- Tensorflow (1.4.1)
- gene expression: allforDNN_ge_sample.txt
- DNA methylation: allforDNN_me_sample.txt
- data preprocessing
- Split_Inputdata.py
- feature selection
- 01 investigate_DEG_all data.R
- 02 Annotate_DMP.py
- hyperparameter search
- BayesianOpt_HpParm_Search.py
- prediction
- AD_Prediction_ML.py
- AD_Prediction_DNN.py