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saisaitian's Projects

aidps icon aidps

Artificial intelligence-derived prognostic signature

alzgpsnet icon alzgpsnet

Multimodal single-cell/nucleus RNA-sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing in Alzheimer’s disease

bayesynergy icon bayesynergy

An R package for Bayesian semi-parametric modelling of in-vitro drug combination experiments

benchmark_control icon benchmark_control

This work comprehensively provides performance comparisons of 16 Sample-Specific network Control (SSC) analysis frameworks based on the combination of four sample-specific network reconstruction methods and four representative structural control methods corresponding to the two steps of SSC on the real-world biological data.

bhlhe40 icon bhlhe40

Code for "Single-Cell RNA Sequencing and Spatial Transcriptomics Analysis Identify BHLHE40 as A Key Transcription Factor for EMT in Metastatic Colorectal Cancer"

brca_cell_atlas icon brca_cell_atlas

Data processing and analysis related code associated with the study "A single-cell and spatially resolved atlas of human breast cancers".

brcanmolsub_targets icon brcanmolsub_targets

Scripts for my doctoral thesis: Search for new therapeutic targets for breast cancer molecular subtypes

cadr icon cadr

Analysis of tripartite drug - biofeature - adverse reaction networks for identification of combinatorial drug adverse effects

cancer_network_control icon cancer_network_control

This packge is a platform to identify personalized driver genes by integrating different single sample network construction methods and different structure based network control principles.

ccrcc_mos icon ccrcc_mos

code and raw data for the project of ccRCC multi-omics subtypes

cellbox icon cellbox

CellBox: Interpretable Machine Learning for Perturbation Biology

cellot icon cellot

Learning Single-Cell Perturbation Responses using Neural Optimal Transport

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