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I'm currently working on my PhD at Harvard University where I am developing methods for the analysis of single-cell genomics data. I also work on methods for CRISPR-Cas9-based genome-editing tools (like base-editing) to study cancer progression. My PhD work is funded by an NIH F31 award through the NCI and focuses on applying innovations in deep learning to analogous problems in the analysis of single-cell data. You can read more about me and my studies at my website.

I am passionate about and interested in:

  • 🧿 (single-cell) epigenomics and chromatin biology
  • 🧬 Functional annotation of variation in the human genome
  • 🧮 Deep learning
  • ✂️ Functional CRISPR studies
  • 🧠 Psychiatric disorders
  • 🧫 Cancer biology
  • 🐍 Implementing open-source tools for genomics in python.
  • 🎨 Computer graphics art

Links

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Repos and software libraries


Deep learning

torch-adata-logoneural-diffeqs-logotorch-composerannoyance-logo

Bioinformatics: CRISPR and other assays (single-cell and bulk)

cell-tools-logoseq-toolkit-logosglib-logoann_nmf-logo

Python developer utility packages and plotting

pysdk-logovinplots-logolicorice-logo



For tutorials and resources: link

GitHub Stats


Selected Publications and preprints


  • Michael E. Vinyard, et al. . Nat. Chem. Biol. DOI: 10.1038/s41589-019-0263-0 (2019).
  • Chen, H., Lareau, C.†, Andreani, T.†, Michal E. Vinyard†, et al. . Genome Biol. DOI: 10.1186/s13059-019-1854-5 (2020).
  • GitHub
  • Huidong Chen, Jayoung Ryu, Michael E. Vinyard, Adam Lerer, & Luca Pinello. . bioRxiv, DOI: 2021.2010.2017.464750 (2021).
  • GitHub
  • docs
  • L. Wang†, Q. Zhang†, Q. Qin†, N. Trasanidis†, Michael E. Vinyard†, et al., . Curr. Opin. in Syst. Biol. ISSN 2452-3100. DOI: 10.1016/j.coisb.2021.03.006 (2021).
  • Stein, D.†, Chen, H.†, Vinyard, M.E.†, et al. . Front. genet. DOI: 10.1101/2020.07.30.229534 (2021).
  • GitHub
  • singlecellVR.com

made-with-Markdown GitHub forks GitHub stars

Dyanmically generated stats are implemented from GitHub Readme Stats

† denotes equal contribution

Michael Vinyard's Projects

abcparse icon abcparse

A better base class that handles parsing local arguments.

ann_nmf icon ann_nmf

AnnData wrapper of the ARD-NMF module from SignatureAnalyzer

annoyance icon annoyance

AnnData-compatible wrapper of Spotify's annoy library.

autodevice icon autodevice

Automatically assign devices in-line with pytorch code

cell-ann icon cell-ann

Cell approximate nearest neighbors (ANN)

flexinet icon flexinet

flexinet: flexible torch neural network composition

genomeio icon genomeio

Genomics-catered read / write functions

gtfast icon gtfast

Lift annotations from a GTF file to an adata object.

keops icon keops

KErnel OPerationS, on CPUs and GPUs, with autodiff and without memory overflows

licorice icon licorice

A python utility library for creating and printing more elegant strings.

pool-sharq icon pool-sharq

Python wrapper for the Broad Institute GPP's poolq software

pylacroix icon pylacroix

A python color palette for those that love sparkled beverages.

sglib icon sglib

guideID: python tools to find PAM sequences

vinplots icon vinplots

Michael E. Vinyard's python plotting assistant

webfiles icon webfiles

Download files hosted on the internet and parse with python

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