Great overlap between the arcuate fasciculus (AF) and the superior longitudinal fasciculus (SLF) II about tractseg

[yutinghe99]

Hello @giovannividetta ,

Thank you for your information, it's very helpful and answers my confusion.

Best wishes,
Yuting

[giovannividetta]

Hello @yutinghe99!

I try to answer your question having a bit knowledge of white matter (WM) neuroanatomy. I have already segmented AF and SLF in my academic carreer.

According to neuronatomy AF can be considered a part of SLF, which is defined as a complex WM system composed of several subsegments. Focusing on AF and SLF II it is normal a partial voxel overlapping due to their neuroanatomical proximity within the human brain: SLF II is localized nearby the dorsal portion of AF (references: https://doi.org/10.1038/npre.2011.5549.1; https://doi.org/10.1016/j.neuroimage.2019.116439). Morevoer, you should bear in mind that when you segment WM fascicles there are several neuroanatomical constraints (e.g.: crossing fibers) which can not be fully managed and may impact the final result. For this reason often it is challenging to clearly distinguish voxels belonging to one fascicle or another.

I hope I have helped you!