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Issue with R script about clinvar HOT 3 CLOSED

VivekTodur avatar VivekTodur commented on August 22, 2024
Issue with R script

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Comments (3)

kristjaneerik avatar kristjaneerik commented on August 22, 2024

I believe this is the error I was seeing with the latest update from ClinVar at #18. The R script tries to select columns from the variant summary table that are not there (but used to be).

There is currently no fix, other than to use older ClinVar data.
For this download the ClinVar XML and variant summary table.
Then run e.g.:

python master.py \
    -R <hg19.fa> \
    -E ExAC.r0.3.1.sites.vep.vcf.gz \
    -X ClinVarFullRelease_2016-09.xml.gz \
    -S variant_summary_2016-09.txt.gz

The R script is broken with data from 2016-10 onward it seems.

from clinvar.

VivekTodur avatar VivekTodur commented on August 22, 2024

Thanks, it works fine now with older data...

from clinvar.

bw2 avatar bw2 commented on August 22, 2024

#21 from @XiaoleiZ has fixed parsing for the new datafiles, so we're back to making up-to-date releases.

from clinvar.

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