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lichenbiostat's Projects

3dpredictor icon 3dpredictor

3DPredictor - a computational approch to predict spatial interactions of chromatin based on epigenetic data

abc icon abc

Allele-specific Binding from Chip-seq

abide icon abide

ABIDE Preprocessed Initiative

adni-netwas icon adni-netwas

Repository associated with Song et al. manuscript describing a Network-wide Association Study of ADNI Cohorts.

ampad-diffexp icon ampad-diffexp

Code base for performing covariate adjustments and differential expression analysis of the RNAseq data from AMP-AD.

aparent icon aparent

APA Regression Net - Predict and Engineer Alternative Polyadenylation

aqua-hichip icon aqua-hichip

Bioinformatic tools (R scripts) for the analysis of Absolute Quantification of Architecture (AQuA-HiChIP) style data.

aspu icon aspu

An R package for adaptive sum of powered score test(ASPU) in genetic association studies.

atmpra icon atmpra

Analysis Toolset for Massively Parallel Reporter Assay data

augmentor icon augmentor

Image augmentation library in Python for machine learning.

basenji icon basenji

Sequential regulatory activity predictions with deep convolutional neural networks.

basset icon basset

Convolutional neural network analysis for predicting DNA sequence activity.

benchmarking_variant_callers icon benchmarking_variant_callers

In this study, we perform systematic comparative analysis of seven widely-used SNV-calling methods, including SAMtools, the GATK Best Practices pipeline, CTAT, FreeBayes, MuTect2, Strelka2 and VarScan2, on both simulated and real single-cell RNA-seq datasets. We evaluate the performances of these tools in different read depths, genomic contexts, functional regions and variant allele frequencies.

bichrom icon bichrom

Interpretable bimodal network for transcription factors binding site prediction

bioinfor-deepatt icon bioinfor-deepatt

DeepATT, a hybrid deep neural network method for identifying functional effects of DNA sequences.

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