krishan57gupta Goto Github PK
Name: Krishan Gupta
Type: User
Bio: I am a research scholar working with the advisor Dr Debarka Sengupta, Computer Science and Center for Computational Biology Department, IIIT Delhi.
Location: Delhi, India
Name: Krishan Gupta
Type: User
Bio: I am a research scholar working with the advisor Dr Debarka Sengupta, Computer Science and Center for Computational Biology Department, IIIT Delhi.
Location: Delhi, India
Beta-Poisson model for single-cell RNA-seq data analyses
DOSeq - Modeling expression drop-out for analysis of scRNA-Seq data. DOSeq takes read count matrix and factor for drop-out ratio as input and return the read count matrix with dropout. Here input parameter factor indicates drop-out ratio in expression matrix.
GitFlow test
The goal of iCTC is to detect whether peripheral blood cells have CTCs (circulating tumor cell) or not.
survival of patients using ors on TCGA data
ROSeq - A rank based approach to modeling gene expression with filtered and normalized read count matrix. Takes in the complete filtered and normalized read count matrix, the location of the two sub-populations and the number of cores to be used.
python project
Single-Cell Analysis in Python. Scales to >1M cells.
cell-gene coembedding and analysis pipeline for single cell transcriptomics data
A prominent clinical symptom of 2019-nCoV infection is hyposmia/anosmia (decrease or loss of sense of smell), along with general symptoms such as fatigue, shortness of breath, fever, and cough. The identity of the cell lineages that underpin infection associated with loss of olfaction could be critical for the diagnostics/clinical management of 2019-nCoV infected individuals. Angiotensin I Converting Enzyme 2 (ACE2), and Transmembrane protease serine 2 (TMPRSS2) are emerging as associated host receptors vital for viral entry. Accordingly, the ongoing medical examinations and the autopsy reports of the deceased individuals strongly corroborate with the organ/cell-type-specific expression of ACE2, TMPRSS2, and other putative viral entry-associated genes. To determine the cellular basis of anosmia upon 2019-nCoV infection, we employed a targeted bioinformatic analysis of single-cell expression profiles of human olfactory epithelium cell-types. Our results underscored selective expression of these viral entry-associated genes in a subset of sustentacular cells, Bowman’s gland cells, and stem cells of the olfactory epithelium. Co-expression analysis of ACE2 and TMPRSS2 and protein-protein interaction among the host and viral proteins elected regulatory cytoskeleton protein-enriched sustentacular cells as the most vulnerable cell-type of the olfactory epithelium. Furthermore, expression, structural and docking analyses of these viral-entry moieties revealed the potential risk of olfactory dysfunction in four additional mammalian species, revealing an evolutionarily conserved susceptibility. In summary, our findings suggest the molecular and cellular rationale of loss of smell in 2019-nCoV infected patients.
Ultrasound Placental image texture Analysis for prediction of Hypertension during pregnancy using Artificial intelligence Research
A declarative, efficient, and flexible JavaScript library for building user interfaces.
🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.
TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
An Open Source Machine Learning Framework for Everyone
The Web framework for perfectionists with deadlines.
A PHP framework for web artisans
Bring data to life with SVG, Canvas and HTML. 📊📈🎉
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
Some thing interesting about web. New door for the world.
A server is a program made to process requests and deliver data to clients.
Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.
Some thing interesting about visualization, use data art
Some thing interesting about game, make everyone happy.
We are working to build community through open source technology. NB: members must have two-factor auth.
Open source projects and samples from Microsoft.
Google ❤️ Open Source for everyone.
Alibaba Open Source for everyone
Data-Driven Documents codes.
China tencent open source team.