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JiscaH avatar JiscaH commented on August 19, 2024

Oops! That shouldn't happen obviously. How many individuals & SNPs are in the dataset? I will make a mock dataset tomorrow (European time) to see if I can reproduce the issue.

You could try the following options when running sequoia():

  • FindMaybeRel = FALSE (if you changed the default)
  • CalcLLR = FALSE (although I don't think the problem lies there)
  • quiet = 'verbose' (to get more detail on where exactly the crash is happening)

I assume this is sequoia version 1.3.3, as on CRAN? Version 1.3.6 on here may or may not have the same issue, but I don't have access to a Mac to compile it for you.

Cheers,
Jisca

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walla296 avatar walla296 commented on August 19, 2024

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JiscaH avatar JiscaH commented on August 19, 2024

Hello Liz,
I've used dataset of that size & larger on many occasions (up to 6000 indiv), so that in itself can't be the cause of the problem!

If at all possible, could you email the data to jisca.huisman @ gmail.com ? Needless to say I'll treat the data confidentially.

Jisca

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walla296 avatar walla296 commented on August 19, 2024

Okay, thanks. Just sent you the data file. The original run parameters were: MaxSibIter = 10, MaxMismatch = 10, UseAge = "yes", FindMaybeRel = TRUE, CalcLLR = TRUE, quiet = FALSE.
After changing to FindMaybeRel = FALSE, CalcLLR = FALSE , quiet = 'verbose', as you suggested, RStudio still aborted the session. the following was displayed just before the crash:
Round 2 start
Finding pairs...
Clustering...
Merge clusters...
Sibship parent replacement...
Grow clusters...

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