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Geoff Adams's Projects

ancombc icon ancombc

Differential abundance (DA) and correlation analyses for microbial absolute abundance data

bhglm icon bhglm

BhGLM (Bayesian hierarchical GLMs and survival models)

deseq2 icon deseq2

Differential gene expression analysis based on the negative binomial distribution

devis icon devis

DEvis: an R package for aggregation and visualization of differential expression data

export icon export

R package for streamlined export of graphs and data tables.

figaro icon figaro

An efficient and objective tool for optimizing microbiome rRNA gene trimming parameters

ggpubr icon ggpubr

'ggplot2' Based Publication Ready Plots

gmpr icon gmpr

GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data

gneiss icon gneiss

compositional data analysis toolbox

maaslin2 icon maaslin2

MaAsLin2: Microbiome Multivariate Association with Linear Models

metabarpipe icon metabarpipe

an R package to process raw metabarcoding data into a phyloseq object using a single command

metacoder icon metacoder

Parsing, Manipulation, and Visualization of Metabarcoding/Taxonomic data

metalonda icon metalonda

METAgenomic LONgitudinal Differential Abundance method

metaphlan icon metaphlan

MetaPhlAn is a computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data

metarna-seq icon metarna-seq

Custom scripts for creating and annotating multispecies bacterial metagenomes

microbiomeseq icon microbiomeseq

An R package for microbial community analysis in an environmental context

microbiomeutilities icon microbiomeutilities

The is mostly a wrapper tool using phyloseq and microbiome R packages. Apart for some simple scripts, this package has a single function generates a HTML report with preliminary QC, Alpha Diversity, Ordination and Composition analysis of OTU tables.

micropower icon micropower

power estimation for microbiome studies analyzed with pairwise distances and PERMANOVA

nbzimm icon nbzimm

NBZIMM (Negative Binomial and Zero-Inflated Mixed Models)

ng-tax icon ng-tax

NG-Tax is an improved pipeline for 16S rRNA gene amplicon sequencing data. Several novel steps ensure improved robustness against errors associated with technical aspects of these studies, such as PCR protocols, choice of 16S rRNA gene variable region and variable rates of sequencing error. The commonly reported problems such as many un- or poorly classified OTUs, inflated richness and diversity, taxonomic profiles that do not match the expected ones, region dependent taxonomic classification and results being highly dependent on minor changes in the experimental setup have been tackled with NG-Tax.

phyloseq icon phyloseq

phyloseq is a set of classes, wrappers, and tools (in R) to make it easier to import, store, and analyze phylogenetic sequencing data; and to reproducibly share that data and analysis with others. See the phyloseq front page:

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