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chenyongrowan's Projects

degage icon degage

DEGage is a novel model-based method for gene differential expression analysis between two groups of scRNA-seq count data. It employs a novel family of discrete distributions for describing the difference of two NB distributions (named DOTNB).

dotnb icon dotnb

The DOTNB repository is a collection of code files that implement DOTNB across several programming languages. The DOTNB is the distribution for the Difference Of Two Negative Binomial distributions, i.e., Z=X-Y ~ DOTNB (λ_1,λ_2,p_1,p_2), where X ~ NB(λ_1,p_1 ) and Y ~ NB(λ_2,p_2 ).

gatekeeper icon gatekeeper

GATEkeeper is an effective pipeline to detect and annotate mutations. Based on large number of sequenced COVID-19 genomes, GATkepper pipeline provides a useful tool for deep analysis of virus mutations, mutation tracing and statistical analysis.

logicbrain icon logicbrain

An advanced generative AI system focusing on querying, modeling and simulating complex biological systems

sctiger icon sctiger

The Single-cell Temporal Inference of Gene Regulatory (scTIGER) Networks method is a computational method designed to predict gene regulatory networks (GRNs) using paired datasets of case versus control experiments.

sctiger2.0 icon sctiger2.0

We are updating scTIGER for inferring GRN from single dataset and case-vs-control dataset.

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