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The Wang lab at AMSS's Projects

3scover icon 3scover

3SCover is a method to identify safeguard TF from cell type -TF network by an extended mimimum set cover model.

cregulon icon cregulon

cRegulon is an optimization model to identify combinatorial regulon from single cell expression and chromatin accessibility data.

guidingnet icon guidingnet

GuidingNet is a method to reveal transcriptional cofactor and predict binding for DNA methyltransferase by network regularization.

hreg-cncc icon hreg-cncc

hReg-CNCC is a high-quality Regulatory network of Cranial Neural Crest Cell (CNCC), built by consensus optimization.

mutnet icon mutnet

A heterogeneous network embedding based method by integrating genomic data with genes’ biological processes including protein-protein interactions and pathways.

re-goa icon re-goa

A tool for non-coding genomic regions function enrichment analysis based on Regulatory Elements Gene Ontology Annotation (RE-GOA)

rp3 icon rp3

RP3 (RNA Polymerase II Pausing Prediction) is a method for predicting transcriptional elongation Pol II pausing by integrating multi-omics data

sctim icon sctim

scTIM is a convenient tool for cell-type indicative marker detection based on single cell RNA-seq data

specloop icon specloop

SpecLoop is a method for predicting cell type-specific chromatin loops via transcription factor cooperation.

specvar icon specvar

SpecVar is a convenient tool for estimating interpretable genetic correlation of human complex traits and annotating the SNPs with context specific regulatory networks

vpeca icon vpeca

vPECA is a Variants interpretation method by Paired Expression and Chromatin Accessibility data which can identify active and active selected regulatory elements and their gene regulatory network.

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